Doctor's Best Lutein con suplemento de Lutemax y Meso-Zeaxantina, DRB-00370, 1

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Doctor's Best Lutein con suplemento de Lutemax y Meso-Zeaxantina, DRB-00370, 1.
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. Más información del producto Leer más *These statements have not been evaluated by the Food and Drug Administration. This product in not intended to diagnose, treat, cure or prevent any disease. ** Lutein with Lutemax Registered Doctor’s Best Lutein with Lutemax** supplies lutein, zeaxanthin, and meso-zeaxanthin, the three carotenoid nutrients that are concentrated in the eye. These carotenoids are excellent antioxidants which naturally accumulate in the retina and support healthy light-sensing and glare control.* Lutein with Lutemax** helps protect against photo-damage from blue light. Blue light is the most hazardous component of the visible light spectrum. Research has shown that lutein has a protective effect against blue light.* Formulated for those who are exposed to sunlight, indoor lighting, computers, TVs and other digital devices.* Leer más What are the benefits of Lutein? - Helps enhance visual function* - Helps promote macular health* - Protects eyes from damaging UV and Blue Light* Why take Lutein? - Supplies lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ), three carotenoid nutrients with clinically proven benefits for vision and eye health* - Sustainably-produced from Marigold flowers, naturally rich in L, Z and MZ* - Supports eyes during aging* How does it work? - Lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) work synergistically to promote eye health.* - The L+Z+MZ triad acts as a yellow filter, screening out shortwave blue light, helping protect eyes and ensuring clear vision* - L+Z+MZ are also potent free radical neutralizers that continue to the body’s spectrum of antioxidant defenses* Leer más Ampliar Leer más Doctor’s Best Lutein Featuring Lutemax supplies lutein (L, for short), zeaxanthin (Z), and meso-zeaxanthin (MZ), three carotenoid nutrients with clinically proven benefits for vision and eye health.1-7 This carotenoid triad is highly concentrated in the retina and other eye tissues and in the brain.8 Preliminary studies suggest they can enhance brain functions.8,9 Both L and Z are vitamin-like nutrients for humans and non-human primates, such as monkeys.7 For monkeys, totally removing L and Z from the diet results in impaired visual function.11 The standard American diet provides very low intakes—only about 1-3 mg per day of L plus Z, coming mostly from vegetables and fruits.12 Findings from clinical trials suggest higher intakes could provide more support for eye and brain health.5,6 L, Z, and MZ are classified as xanthophyll carotenoids because their molecules contain oxygen, built into hydroxyl groups.13 This gives them properties distinct from beta-carotene and many other dietary carotenoids, and makes them especially suited to occupy unique positions within cell membranes.13,14 All cells are organized around membranes, which are thin but continuous molecular sheets that form the cell’s outer border along with functionally specialized compartments within the cell’s interior.14 Located in the retina of the eye are cells that have L, Z and MZ concentrated in their membranes. They provide effective protection against light damage to the retina, but are also biochemically involved in the processes that generate vision.13,15 The L+Z+MZ triad acts as a yellow filter that screens out shortwave 'blue' light, thereby helping ensure that vision is relatively free of glare and haze.5,16,17 They also contribute to such fundamental cell processes as gene regulation, cell growth and maturation, and cell to cell signaling.16 Lutein and zeaxanthin are at least 500 times more concentrated in the retina than in the blood, due to sets of proteins that bind tightly with them, transport them from the blood into the retinal tissue, then deliver them into light-sensing cells within the retina.18 Lutein predominates in the eye’s iris and lens as well as the retina. Zeaxanthin tends to accompany lutein and is most concentrated at the retina’s periphery. Meso-zeaxanthin is generated from lutein in the macula, and is highly concentrated in the central retinal zone that receives the most light and is therefore most vulnerable to light damage.6 The collective accumulations of L+Z+MZ in the macula give it an intense yellowish-orange color, a “macular pigment” (MP) that can be conveniently measured using optical methods as the MP density.19 L+Z+MZ levels in the retina closely match the MP density, so that MP density is widely used as a bridge to link vision function with inferred macular L+Z+MZ levels. Enhances Visual Function* - The density of macular pigment in young, healthy subjects has been linked to the eye’s capacity to cope with glare, photostress recovery (time needed to recover sight following an intense light exposure), and other visual challenges.7 Supplementing the diet with L+Z+MZ can improve visual performance and help counter such challenges.1,2,5 In a clinical trial with 39 healthy subjects, aged 17-41 years and with no history of vision problems, each received 10 mg of L and 2 mg of Z per day, for 6 months.1 Visual performance under conditions of high glare and photostress (very high intensity light exposure) improved, and was significantly correlated with MP density increase, that is, with buildup of L+Z+MZ in the retina. Visual performance showed significant improvement by 4 months into the trial. In another trial,2 121 healthy subjects aged 18-41 years were divided into a group that received 10 mg of L and 1 mg of Z per day (the active group), and a placebo group. Over the 12-month dosing period MP significantly increased. From self-scoring on a questionnaire, the L+Z group scored significantly better than placebo for night driving against oncoming headlights. These researchers then further analyzed their data, to compare the one-third of active group subjects who achieved the highest MP density at 12 months, against the one-third with the lowest MP density.2 The high-MP subgroup had 30% more improved contrast sensitivity under high glare, compared to the low-MP subgroup. On the questionnaire the high-MP subgroup reported significantly better capacity to deal with sudden changes in illumination (light/dark adaptation) than the low-MP subgroup. The L+Z+MZ triad also helps protect the eye’s lens against sustaining damage from light energy as it concentrates light onto the retina. Findings from two meta-analyses (pooled analyses of data from multiple clinical trials) suggest that higher intakes of L and Z contribute to maintaining the lens structural integrity.3,4 Two leading vision researchers described L+Z+MZ as 'analogous to internal sunglasses' that help counter glare discomfort and disability, shorten photostress recovery times, enhance color contrast, and increase visual range (how far one can see in the distance).5 They discussed just how these nutrients might help baseball players. Looking into the bright sun outdoors, or bright overhead lights in an indoor stadium, can promote glare or cause photostress. Suspended particles in the air can create 'blue haze' that impairs distance vision. These researchers reviewed the considerable evidence that blue-wavelength light, which is most responsible for these effects, is screened out by L+Z+MZ.5 Promotes Macular Health* - The macula is the most central zone of the retina and consequently most directly exposed to light focused on it by the lens. Its MP content helps minimize blue haze and glare, which can degrade the image, while maximizing contrast sensitivity and light/dark adaptation. For the macula and the rest of the retina, the L+Z+MZ triad is a unique asset.17 The cells of the macula have extensive cell membrane networks with high content of polyunsaturated fatty acids, which renders these cells highly vulnerable to free radical attack.9 Further, their intense metabolic activity requires high oxygen levels, which amplifies the free radical threat. L+Z+MZ helps protect the macula and the entire vision system against this threat.17 The L+Z+MZ triad also makes for synergy—these nutrients’ combined protective actions surpass those of any one by itself.20 Their molecules can span the membrane’s entire width, allowing them both to intercept free radicals within the membrane and to help neutralize free radicals in the water-phase 'cytoplasm' at the membrane’s edge.14 Supports the Eyes During Aging* - Macular pigment density declines with age, beginning around age 60.21 Negative lifestyle factors such as cigarette smoking can exacerbate this decline.22 In a study of 484 subjects aged 18 to 70 years, smoking was significantly linked to loss of MP density. Subjects who had never smoked had significantly less MP loss than those who were current smokers. Retinal MP density has been linked to the eye’s lens in later life. A study of 376 individuals aged 18–75 years found that MP density was significantly correlated with the tissue density of the lens.23 For subjects older than 50 years, the higher their macular density the lower was their lens density. Low lens density is healthy because it allows light to pass freely through the lens without damaging the lens tissue itself. The researchers concluded that L and Z intake supports maintenance of healthy eye lenses with age. MZ may be more important for vision than previously assumed. Though supplementation with just L+Z can improve contrast sensitivity and light-dark adaptation,2 the total evidence strongly suggests that MZ is absolutely required for vision.6 Though rare or absent from most diets, MZ makes up fully one-third of the total macular pigment and its abundance at the very center of the macula is a clue to its importance.13 Evidence is growing that L and Z are also important for the brain. First, in-depth studies with monkeys established that the levels of L and Z in the brain can be accurately predicted from their levels in the macular pigment, and this prediction was extended to humans.8,10 From study of human brains it is clear that L and Z are concentrated in the brain’s visual cortex, which does initial processing of visual stimuli, in the motor cortex, which can generate movement in response to visual stimulation; and in the frontal cortex, which helps generate conscious response to visual stimulation.9 Supports the Brain and Brain-Eye Coordination* - L and Z in the human brain may contribute to eye-brain coordination and 'visuomotor' functions (visual and motor cortex coordination). In a study with healthy subjects aged 24-76 years, higher retinal MP density (and by extension, higher brain levels of L and Z) were significantly linked with faster visual-motor response time (time required to respond to an asterisk appearing on a screen).9 Higher MP was also significantly linked to longer “balance time” (length of time a subject could stand on one leg), a measure of motor function. Returning to the baseball analogy5: A batter with faster visual processing speed can 'take more snapshots' of the pitch as it approaches home plate. With less than one-tenth of a second to decide on a 95-mph fastball, the added processing speed from higher daily intake of L+Z+MZ could be helpful to a hitter. This analogy has relevance for anyone wanting to optimize their vision, mind-body coordination or other skills. Another study measured cognitive functions in older adults and correlated them with MP densities.10 For 24 subjects with some cognitive impairment, higher MP density was significantly related to better performance on the MMSE (Mini-Mental Status Examination), on the RBANS (Repeatable Battery for Assessment of Neuropsychological Status), and on specific tests of attention, language ability, and spatial-constructional ability. For 29 subjects without measurable cognitive impairment, higher MP was significantly linked to spatial-constructional ability. There is preliminary evidence that supplementation with L+Z can improve cognition. In a double blind, placebo-controlled trial with healthy women aged 60–80 years,11 11 women were randomly allocated to receive L (12 mg per day) plus Z (about 0.5 mg per day), and 10 women received a placebo, for 4 months. The L+Z group scored higher than the placebo group on verbal fluency — ability to retrieve words from long-term memory in a short period of time. This positive result with small groups makes a case for larger, more in-depth trials with L and Z for brain health. Lutein, zeaxanthin and meso-zeaxanthin are vitamin-like nutrients important for vision, eye-brain coordination, and quality of life. Emotional, chemical, physical, and other stresses of modern living tend to deplete nutrients from the body and consequently increase daily nutritional requirements.25 Doctor’s Best Lutein Featuring Lutemax is sustainably produced from marigold flowers, and is a prudent dietary supplementation option considering that most Americans may be challenged to maintain adequate intakes of these carotenoids in their daily diet. Leer más . Descripción del producto Tamaño:180 Count Doctor de la mejor, mejor luteína, con lutemax, 20 mg, 60 Softgels .