Doctor 's Best hueso eléctrica con bonolive, sin OMG, vegano, sin gluten, última intervensión de...
- Product Code: 1567595453-2764
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$ 47.07
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1.- Tiempo de entrega de 3 a 5 días Hábiles.
2.- Enviamos su compra a cualquier parte del país.
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***** TITULO COMPLETO *****
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Doctor 's Best hueso eléctrica con bonolive, sin OMG, vegano, sin gluten, última intervensión de....
***** DESCRIPCIÓN DEL PRODUCTO *****
.
. Más información del producto Leer más Ampliar * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. **Bone Maker Registered. Doctor’s Best Bone Maker** with Bonolive (olive leaf extract) has been clinically studied to help support bone building cells. Bonolive is a calcium-free bone health supplement to help build bones by supporting osteoblasts, cells that build bones.* Bone Maker** contains olive leaf extract standardized to 40% Oleuropein (active ingredient) versus typical olive leaf extracts that contain only 20%. Oleuropein works in support of two fundamental bone health goals: supporting bone formation and bone strength. Leer más What are the benefits of Bone Maker**? - Easy to swallow in just one small capsule per day.* - Helps increase bone building cells (osteoblasts).* - Helps decrease bone dissolving cells (osteoclasts).* - Helps support bone density.* - Water soluble for superior bioavailability.* Why take Bone Maker**? - BonOlive provides powerful antioxidant support at cellular level.* - BonOlive helps support cardiovascular health.* - BonOlive may improve bone health.* - Bonolive is the only clinically proven olive-based bone supplement. The clinical dose is very small compared to other calcium supplements.* How does it work? - Calcium-free bone health supplement that helps promote the stimulation of bone building cells (osteoblasts).* - Bone Maker** contains olive leaf extract standardized to 40% oleuropein versus typical olive leaf extracts which only contain 20%. Oleuropein works in support of two fundamental bone health goals: promoting bone formation and supporting bone strength.* Leer más Ampliar Leer más The olive tree (Olea europaea) is native to the Mediterranean region and is grown around the world. Olive fruits provide the olive oil which is an essential component of the Mediterranean diet known for being associated with positive outcomes on cardiovascular and overall health.1,2 Historically, olive leaves have been used in folk remedy to improve digestive, cardiovascular, and skin conditions. Scientific findings have found that the overall health beneficial effect of olive oil come from two main phenolic compounds, namely oleuropein and its metabolite, hydroxytyrosol. BonOlive is composed of highly standardized oleuropein extracted from leaf olive. Oleuropein was found to be one of the major constituents of olive leaves that has shown to be a potent antioxidant endowed with many beneficial health properties.3,4,5,6. BonOlive provides powerful antioxidant support at cellular level* - In the past years, interest in natural antioxidants as bioactive components of foods has been rising. The positive effects of diets rich in fruit, vegetables and olive oils on overall health have been attributed partly to certain compound as phenolic compounds.*3 Oleuropein gives the bitterness taste of olive oil but is also the major phenolic compound in olive leaves that has been studied for its antioxidant activity involving in promising results with respect to its effect on human health.*3,5,7 The daily consumption of olive oil in populations that follow the Mediterranean diet, provides enough oleuropein in the body to supply protection against free radicals and lipid peroxidation in humans.*8 The antioxidant abilities, the scavenging abilities, the chemistry and pharmacological aspects of oleuropein have been widely studied and well known.7,9,10. BonOlive helps support cardiovascular health* - For decades, the Mediterranean diet has been considered to be one of the most healthy. In the 1960s, scientific works started to observe the positive effect on overall cardiovascular health in population that followed the Mediterranean diet.*11 Olive oil is the most popular dietary lipid from the Mediterranean diet and much of the evidence of its beneficial heath is attributed to oleuropein, the major phenolic in olive leaves.12,13,14,15,16. BonOlive may improve bone health* - Epidemiological studies have shown that the incidence of bone loss was lower where the traditional Mediterranean diet with olive oil is widely consumed by the population.17 Moreover, experimental models have been able to show that oleuropein is the phenolic compound from olive leaves involved in hindering the loss of bone mass suggesting its possible key role in improving bone health.*18,19. Pharmacological and Clinical Studies - A randomized crossover study was done to evaluate the effect of phenolic content (as mentioned previously oleuropein is the major phenolic component) of virgin olive oil on endothelial reactivity in humans. The results revealed high intake of phenolic component from olive oil improved endothelium-dependent microvascular vasodilatation and decreased oxidative stress.*20. An animal study designed to test the antioxidative activities of olive leaf oleuropein and its metabolite, hydroxytyrosol was conducted using rats depleted in antioxidant enzymes activities. The results of the administration of oleuropein and hydroxytyrosol rich extracts for 4 weeks suggested that the antioxidative activities of oleuropein and its metabolite might explain the decrease of oxidative stress which is widely associated with cardiovascular complications.*21. The Epic study, an European Prospective Investigation study that included over 20,000 participants, showed that the intake of olive oil and the Mediterranean Diet as an entity could improve cardiovascular health.*11 In the Predimed trial where 187 participants were recruited, the results after a 3-year long trial, showed that participants who followed a Mediterranean Diet rich in olive oil saw a reduction in body weight and had a higher level of plasma antioxidant capacity.*22. In a short-term study that included over 700 participants, results revealed that Mediterranean diet supplemented with olive oil had greater positive outcomes on cardiovascular health than low-fat diets.*23. A double-blind, randomized, parallel and active-controlled clinical study was conducted to evaluate the anti-hypertensive effect of olive leaf extract (standardized to oleuropein) in comparison with an anti-hypertensive medication. Olive leaf extract at the dosage regimen of 500 mg twice daily had the comparable anti-hypertensive activity when compared to an antihypertensive medication. This study also demonstrated the safety and tolerability of the olive leaf extract. The conclusion suggested the role of oleuropein in improving cardiovascular heatlh.*24. The effect of oleuropein and other polyphenols found in olives, on bone formation (using cultured osteoblasts and osteoclasts cells) and on bone loss in ovariectomized mice were evaluated. The results shown that oleuropein may have critical effects on the formation and maintenance of bone and may be a natural alternative in improving bone health.*25. The influence of oleuropein on osteoblastogenesis (process involved in bone remodeling) was studied in an in vitro model using human bone marrow. The results suggested oleuropein could help prevent age-related bone loss hence improve bone health.*17. A study conducted in 34 male participants, was done to evaluate the effect of olive oil intake on circulating osteocalcin, a marker of bone formation. The result showed an increase in level of osteocalcin in males receiving a Mediterranean diet enriched with virgin olive oil compared to those who received a Mediterranean diet enriched with nuts.26 The findings from this study concur with experimental reports that associate the consumption of olive oil and oleuropein with the improvement of bone mass in animal models.*26,27. The bioavaibility of phenolic constituents from an oleuropein-rich olive leaf extract and its acute effect on plasma antioxidant status were evaluated in 16 women who received each 250 mg of olive leaf extract. The results led to the conclusion that the oral dietary intake of olive leaf extract could exert benefits against oxidative stress-related processes such as bone loss.*28. In a double-blind, placebo-controlled study, 64 female participants were randomly assigned to either treatment or placebo groups. For 12 months, participants received daily either the treatment (250 mg/day of olive extract BonOlive + 1000 mg calcium) or placebo (1000 mg/day calcium.) The results led to the conclusion that BonOlive can positively affect serum of osteocalcin levels improving bone health.* This study was able to show improvement of blood lipid profiles in participants that received the olive extract suggesting additional health benefits associated with the intake of BonOlive*29. Scientific References: 1. Covas M, Ruiz-Gutierrez V, De La Torre R, et al. Minor Components of Olive Oil: Evidence to Date of Health Benefits in Humans. Nutr Rev. 2006;64:20-30. 2. Buckland G. and Gonzalez CA. The role of olive oil in disease prevention: a focus on the recent epidemiological evidence from cohort studies and dietary intervention trials. Brit J Nutr. 2015;113:S94-S101. 3. Benavente-Garcia O, Castillo J, Lorente J et al. Antioxidant activity of pheolics extracted from Olea europaea L. leaves. Food Chem. 2000;68:457-462. 4. Ghedira K. L'olivier. Phytotherapie. 2008;6:83-89. 5. Barbaro B, Toietta G, Maggio R et al. Effects of the olive-derived polyphenol oleuropein on human health. Int J Mol Sci. 2014;15:18508-15524. 6. Ben Salem M, Affes H, Ksouda K, et al. Pharmacological Activities of Olea europaea Leaves. J Food Processing and Preservation. 2015;39:3128-3136. 7. Wichers HJ, Espin JC and Soler-Rivas C. Oleuropein and related compounds. J Sci Food and Agric. 2000;80:1013-1023. 8. Perona JS, Cabello-Moruno R and Ruiz-Gutierrez V. The role of virgin olive oil components in the modulation of endothelial function. J Nutr Biochem. 2006;17:429-445. 9. Tuck KL and Hayball PJ. Major phenolic compounds in olive oil: metabolism and health effects. J Nutr Biochem. 2002;13:636-644. 10. Tripoli E, Giammanco M, Tabacchi G et al. The phenolic compounds of olive oil: sructure, biological activity and beneficial effects on human health. Nutr Res Rev. 2005;18:98-112. 11. Psaltopoulou T, Naska A, Orfanos P, and al. Olive oil, the Mediterranean diet, and arterial blood pressure: the Greek European Prospective Investigation into Cancer and Nutrition (EPIC) study. The American journal of clinical nutrition. 2004;80:1012. 12. Covas MI. Olive oil and the cardiovascular system. Pharmacol Res. 2007;55:175-186. 13. Zacharias E. The Mediterranean Diet: A Clinician's Guide for Patient Care. Publisher: Springer New York. 2012. 14. Waterman E. and Lockwood B. Active components and clinical applications of olive oil. Alternative medicine review : J Clin Ther. 2007;12:331. 15. Omar SH. Oleuropein in olive and its pharmacological effects. Scientia pharmaceutica. 2010;78:133-154. 16. Preedy VR, Watson RR. Olives and Olive Oil in Health and Disease Prevention. 1st ed. Amsterdam; Boston: Elsevier/Academic Press; 2010;2013. 17. Santiago-Mora R, Casado-Diaz A. De Castro MD et al. Oleuropein enhances osteoblastogenesis and inhibits adipogenesis: the effect on differenciation in stem cells derived from bone marrow. Osteoporosis Int. 2011;22:675-684. 18. Puel C, Mathey J, Agalias A et al. Dose-response study of effect of oleuropein, an olive oil polyphenol, in an ovariextomy/inflammation experimental model of bone loss in the rat. Clin Nutr. 2006;25:859-868. 19. García-Martínez O, Rivas A, Ramos-Torrecillas J, et al. The effect of olive oil on osteoporosis prevention. Int J Food Sci Nutr. 2014;65:834-840. 20. Ruano J, Lopez-Miranda J, Fuentes F et al. Phenolic content of virgin olive oil improves ischemic reactive hyperemia in hypercholesterolemic patients. JACC. 2005;46:1686-1868. 21. Jemai H, El Feki A, and Sayadi S. Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats. J Agric Food Chem. 2009;57:8798-8804. 22. Razquin C, Martinez JA, Martinez-Gonzalez MA et al. A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain. Eur J Clin Nutr. 2009;63:1387-1393. 23. Estruch R, Martinez-Gonzalez MA, Corella D, et al. Effects of a Mediterranean-style diet on cardiovascular risk factors. Ann Intern Med. 2006;145:1-11. 24. Susalit E, Agus N, Effendi I, et al. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: Commparison with Captopril. Phytomedicine. 2011;18:251-258. 25. Hagiwara K, Goto T, Araki M, et al. Olive polyphenol hydroxytyrosol prevents bone lossEur J Pharmacol. 2011;662:78-84. 26. Fernández-Real JM, Bulló M, Moreno-Navarrete JM, et al. A Mediterranean diet enriched with olive oil is associated with higher serum total osteocalcin levels in elderly men at high cardiovascular risk. J Clin Endocr Metab. 2012;97:3792-3798. 27. Liu H, Huang H, Li B, et al. Olive oil in the prevention and treatment of osteoporosis after artificial menpause. Clin Interv in Aging. 2014;9:2087-2094. 28. Garcia-Villalba R, Larrosa M, Possemiers S, et al. Bioavaibility of phenolics from an oleuropein-rich olive (Olea europaea) leaf extract and its acute effect on plasma antioxidant status: comparison between pre- and postmenopausal women. Eur J Nutr. 2014;53:1015-1027. 29. Filip R, Possemiers S, Heyerick A, et al. Twelve-month consumption of a polyphenol extract from olive (Olea europaea) in a double blind, randomized trial increases serum total osteocalcin levels and improves serum lipid profiles in postmenopausal women with osteopenia. J Nutr Health Aging. 2015;19:78-86. Leer más . Descripción del producto Bone eléctrica con bonolive 250 mg 60 vegcapdescription Los médicos con mejor porcelana eléctrica bonolive es un suplemento calcium-free salud ósea que ayuda a promover la estimulación de hueso Building celdas (osteoblasts). bonolive es la única clínicamente probado olive-based Bone Suplemento. La clínica Dosis es muy pequeña en comparación con otros suplementos de calcio.* Bone eléctrica contiene extracto de hoja de olivo estandarizado al 40% oleuropeína Versus energético extractos de hoja de olivo que sólo contienen 20%. oleuropeína funciona en apoyo de dos objetivos de salud ósea promoviendo la formación de hueso y fundamentales Supporting Bone fuerza.* nongluten Sin gluten Libre de soja Vegan Uso sugerido como un suplemento dietético tomar 1 Cápsula diaria, con o sin alimentos, o como recomendado por un nutritionally-informed médico. , o como dirigido por su profesional de la salud. Suplemento hechos servir Tamaño: 1 vcapsservings por contenedor: 60 Cantidad por servir% Valor Diario * * * bonolive (de olivo (Olea europaeal.) Leaf ext, estandarizado para contener 40% ooleuropein) 250 mg * * * Valor diario no establecido * * *% los valores diarios están basados en una dieta de 2.000 calorías Otros ingredientes: celulosa modificada (cápsula) vegetariano, microcristalino celulosa, dióxido de silicio, estearato de magnesio (Fuente vegetal) Advertencias: Mantener fuera del alcance de los niños. Como con todos los suplementos dietético, consulte a su profesional de la salud antes de su uso. Consulte la etiqueta del producto para obtener más información. .
1.- Tiempo de entrega de 3 a 5 días Hábiles.
2.- Enviamos su compra a cualquier parte del país.
.
.
***** TITULO COMPLETO *****
.
Doctor 's Best hueso eléctrica con bonolive, sin OMG, vegano, sin gluten, última intervensión de....
***** DESCRIPCIÓN DEL PRODUCTO *****
.
. Más información del producto Leer más Ampliar * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. **Bone Maker Registered. Doctor’s Best Bone Maker** with Bonolive (olive leaf extract) has been clinically studied to help support bone building cells. Bonolive is a calcium-free bone health supplement to help build bones by supporting osteoblasts, cells that build bones.* Bone Maker** contains olive leaf extract standardized to 40% Oleuropein (active ingredient) versus typical olive leaf extracts that contain only 20%. Oleuropein works in support of two fundamental bone health goals: supporting bone formation and bone strength. Leer más What are the benefits of Bone Maker**? - Easy to swallow in just one small capsule per day.* - Helps increase bone building cells (osteoblasts).* - Helps decrease bone dissolving cells (osteoclasts).* - Helps support bone density.* - Water soluble for superior bioavailability.* Why take Bone Maker**? - BonOlive provides powerful antioxidant support at cellular level.* - BonOlive helps support cardiovascular health.* - BonOlive may improve bone health.* - Bonolive is the only clinically proven olive-based bone supplement. The clinical dose is very small compared to other calcium supplements.* How does it work? - Calcium-free bone health supplement that helps promote the stimulation of bone building cells (osteoblasts).* - Bone Maker** contains olive leaf extract standardized to 40% oleuropein versus typical olive leaf extracts which only contain 20%. Oleuropein works in support of two fundamental bone health goals: promoting bone formation and supporting bone strength.* Leer más Ampliar Leer más The olive tree (Olea europaea) is native to the Mediterranean region and is grown around the world. Olive fruits provide the olive oil which is an essential component of the Mediterranean diet known for being associated with positive outcomes on cardiovascular and overall health.1,2 Historically, olive leaves have been used in folk remedy to improve digestive, cardiovascular, and skin conditions. Scientific findings have found that the overall health beneficial effect of olive oil come from two main phenolic compounds, namely oleuropein and its metabolite, hydroxytyrosol. BonOlive is composed of highly standardized oleuropein extracted from leaf olive. Oleuropein was found to be one of the major constituents of olive leaves that has shown to be a potent antioxidant endowed with many beneficial health properties.3,4,5,6. BonOlive provides powerful antioxidant support at cellular level* - In the past years, interest in natural antioxidants as bioactive components of foods has been rising. The positive effects of diets rich in fruit, vegetables and olive oils on overall health have been attributed partly to certain compound as phenolic compounds.*3 Oleuropein gives the bitterness taste of olive oil but is also the major phenolic compound in olive leaves that has been studied for its antioxidant activity involving in promising results with respect to its effect on human health.*3,5,7 The daily consumption of olive oil in populations that follow the Mediterranean diet, provides enough oleuropein in the body to supply protection against free radicals and lipid peroxidation in humans.*8 The antioxidant abilities, the scavenging abilities, the chemistry and pharmacological aspects of oleuropein have been widely studied and well known.7,9,10. BonOlive helps support cardiovascular health* - For decades, the Mediterranean diet has been considered to be one of the most healthy. In the 1960s, scientific works started to observe the positive effect on overall cardiovascular health in population that followed the Mediterranean diet.*11 Olive oil is the most popular dietary lipid from the Mediterranean diet and much of the evidence of its beneficial heath is attributed to oleuropein, the major phenolic in olive leaves.12,13,14,15,16. BonOlive may improve bone health* - Epidemiological studies have shown that the incidence of bone loss was lower where the traditional Mediterranean diet with olive oil is widely consumed by the population.17 Moreover, experimental models have been able to show that oleuropein is the phenolic compound from olive leaves involved in hindering the loss of bone mass suggesting its possible key role in improving bone health.*18,19. Pharmacological and Clinical Studies - A randomized crossover study was done to evaluate the effect of phenolic content (as mentioned previously oleuropein is the major phenolic component) of virgin olive oil on endothelial reactivity in humans. The results revealed high intake of phenolic component from olive oil improved endothelium-dependent microvascular vasodilatation and decreased oxidative stress.*20. An animal study designed to test the antioxidative activities of olive leaf oleuropein and its metabolite, hydroxytyrosol was conducted using rats depleted in antioxidant enzymes activities. The results of the administration of oleuropein and hydroxytyrosol rich extracts for 4 weeks suggested that the antioxidative activities of oleuropein and its metabolite might explain the decrease of oxidative stress which is widely associated with cardiovascular complications.*21. The Epic study, an European Prospective Investigation study that included over 20,000 participants, showed that the intake of olive oil and the Mediterranean Diet as an entity could improve cardiovascular health.*11 In the Predimed trial where 187 participants were recruited, the results after a 3-year long trial, showed that participants who followed a Mediterranean Diet rich in olive oil saw a reduction in body weight and had a higher level of plasma antioxidant capacity.*22. In a short-term study that included over 700 participants, results revealed that Mediterranean diet supplemented with olive oil had greater positive outcomes on cardiovascular health than low-fat diets.*23. A double-blind, randomized, parallel and active-controlled clinical study was conducted to evaluate the anti-hypertensive effect of olive leaf extract (standardized to oleuropein) in comparison with an anti-hypertensive medication. Olive leaf extract at the dosage regimen of 500 mg twice daily had the comparable anti-hypertensive activity when compared to an antihypertensive medication. This study also demonstrated the safety and tolerability of the olive leaf extract. The conclusion suggested the role of oleuropein in improving cardiovascular heatlh.*24. The effect of oleuropein and other polyphenols found in olives, on bone formation (using cultured osteoblasts and osteoclasts cells) and on bone loss in ovariectomized mice were evaluated. The results shown that oleuropein may have critical effects on the formation and maintenance of bone and may be a natural alternative in improving bone health.*25. The influence of oleuropein on osteoblastogenesis (process involved in bone remodeling) was studied in an in vitro model using human bone marrow. The results suggested oleuropein could help prevent age-related bone loss hence improve bone health.*17. A study conducted in 34 male participants, was done to evaluate the effect of olive oil intake on circulating osteocalcin, a marker of bone formation. The result showed an increase in level of osteocalcin in males receiving a Mediterranean diet enriched with virgin olive oil compared to those who received a Mediterranean diet enriched with nuts.26 The findings from this study concur with experimental reports that associate the consumption of olive oil and oleuropein with the improvement of bone mass in animal models.*26,27. The bioavaibility of phenolic constituents from an oleuropein-rich olive leaf extract and its acute effect on plasma antioxidant status were evaluated in 16 women who received each 250 mg of olive leaf extract. The results led to the conclusion that the oral dietary intake of olive leaf extract could exert benefits against oxidative stress-related processes such as bone loss.*28. In a double-blind, placebo-controlled study, 64 female participants were randomly assigned to either treatment or placebo groups. For 12 months, participants received daily either the treatment (250 mg/day of olive extract BonOlive + 1000 mg calcium) or placebo (1000 mg/day calcium.) The results led to the conclusion that BonOlive can positively affect serum of osteocalcin levels improving bone health.* This study was able to show improvement of blood lipid profiles in participants that received the olive extract suggesting additional health benefits associated with the intake of BonOlive*29. Scientific References: 1. Covas M, Ruiz-Gutierrez V, De La Torre R, et al. Minor Components of Olive Oil: Evidence to Date of Health Benefits in Humans. Nutr Rev. 2006;64:20-30. 2. Buckland G. and Gonzalez CA. The role of olive oil in disease prevention: a focus on the recent epidemiological evidence from cohort studies and dietary intervention trials. Brit J Nutr. 2015;113:S94-S101. 3. Benavente-Garcia O, Castillo J, Lorente J et al. Antioxidant activity of pheolics extracted from Olea europaea L. leaves. Food Chem. 2000;68:457-462. 4. Ghedira K. L'olivier. Phytotherapie. 2008;6:83-89. 5. Barbaro B, Toietta G, Maggio R et al. Effects of the olive-derived polyphenol oleuropein on human health. Int J Mol Sci. 2014;15:18508-15524. 6. Ben Salem M, Affes H, Ksouda K, et al. Pharmacological Activities of Olea europaea Leaves. J Food Processing and Preservation. 2015;39:3128-3136. 7. Wichers HJ, Espin JC and Soler-Rivas C. Oleuropein and related compounds. J Sci Food and Agric. 2000;80:1013-1023. 8. Perona JS, Cabello-Moruno R and Ruiz-Gutierrez V. The role of virgin olive oil components in the modulation of endothelial function. J Nutr Biochem. 2006;17:429-445. 9. Tuck KL and Hayball PJ. Major phenolic compounds in olive oil: metabolism and health effects. J Nutr Biochem. 2002;13:636-644. 10. Tripoli E, Giammanco M, Tabacchi G et al. The phenolic compounds of olive oil: sructure, biological activity and beneficial effects on human health. Nutr Res Rev. 2005;18:98-112. 11. Psaltopoulou T, Naska A, Orfanos P, and al. Olive oil, the Mediterranean diet, and arterial blood pressure: the Greek European Prospective Investigation into Cancer and Nutrition (EPIC) study. The American journal of clinical nutrition. 2004;80:1012. 12. Covas MI. Olive oil and the cardiovascular system. Pharmacol Res. 2007;55:175-186. 13. Zacharias E. The Mediterranean Diet: A Clinician's Guide for Patient Care. Publisher: Springer New York. 2012. 14. Waterman E. and Lockwood B. Active components and clinical applications of olive oil. Alternative medicine review : J Clin Ther. 2007;12:331. 15. Omar SH. Oleuropein in olive and its pharmacological effects. Scientia pharmaceutica. 2010;78:133-154. 16. Preedy VR, Watson RR. Olives and Olive Oil in Health and Disease Prevention. 1st ed. Amsterdam; Boston: Elsevier/Academic Press; 2010;2013. 17. Santiago-Mora R, Casado-Diaz A. De Castro MD et al. Oleuropein enhances osteoblastogenesis and inhibits adipogenesis: the effect on differenciation in stem cells derived from bone marrow. Osteoporosis Int. 2011;22:675-684. 18. Puel C, Mathey J, Agalias A et al. Dose-response study of effect of oleuropein, an olive oil polyphenol, in an ovariextomy/inflammation experimental model of bone loss in the rat. Clin Nutr. 2006;25:859-868. 19. García-Martínez O, Rivas A, Ramos-Torrecillas J, et al. The effect of olive oil on osteoporosis prevention. Int J Food Sci Nutr. 2014;65:834-840. 20. Ruano J, Lopez-Miranda J, Fuentes F et al. Phenolic content of virgin olive oil improves ischemic reactive hyperemia in hypercholesterolemic patients. JACC. 2005;46:1686-1868. 21. Jemai H, El Feki A, and Sayadi S. Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats. J Agric Food Chem. 2009;57:8798-8804. 22. Razquin C, Martinez JA, Martinez-Gonzalez MA et al. A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain. Eur J Clin Nutr. 2009;63:1387-1393. 23. Estruch R, Martinez-Gonzalez MA, Corella D, et al. Effects of a Mediterranean-style diet on cardiovascular risk factors. Ann Intern Med. 2006;145:1-11. 24. Susalit E, Agus N, Effendi I, et al. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: Commparison with Captopril. Phytomedicine. 2011;18:251-258. 25. Hagiwara K, Goto T, Araki M, et al. Olive polyphenol hydroxytyrosol prevents bone lossEur J Pharmacol. 2011;662:78-84. 26. Fernández-Real JM, Bulló M, Moreno-Navarrete JM, et al. A Mediterranean diet enriched with olive oil is associated with higher serum total osteocalcin levels in elderly men at high cardiovascular risk. J Clin Endocr Metab. 2012;97:3792-3798. 27. Liu H, Huang H, Li B, et al. Olive oil in the prevention and treatment of osteoporosis after artificial menpause. Clin Interv in Aging. 2014;9:2087-2094. 28. Garcia-Villalba R, Larrosa M, Possemiers S, et al. Bioavaibility of phenolics from an oleuropein-rich olive (Olea europaea) leaf extract and its acute effect on plasma antioxidant status: comparison between pre- and postmenopausal women. Eur J Nutr. 2014;53:1015-1027. 29. Filip R, Possemiers S, Heyerick A, et al. Twelve-month consumption of a polyphenol extract from olive (Olea europaea) in a double blind, randomized trial increases serum total osteocalcin levels and improves serum lipid profiles in postmenopausal women with osteopenia. J Nutr Health Aging. 2015;19:78-86. Leer más . Descripción del producto Bone eléctrica con bonolive 250 mg 60 vegcapdescription Los médicos con mejor porcelana eléctrica bonolive es un suplemento calcium-free salud ósea que ayuda a promover la estimulación de hueso Building celdas (osteoblasts). bonolive es la única clínicamente probado olive-based Bone Suplemento. La clínica Dosis es muy pequeña en comparación con otros suplementos de calcio.* Bone eléctrica contiene extracto de hoja de olivo estandarizado al 40% oleuropeína Versus energético extractos de hoja de olivo que sólo contienen 20%. oleuropeína funciona en apoyo de dos objetivos de salud ósea promoviendo la formación de hueso y fundamentales Supporting Bone fuerza.* nongluten Sin gluten Libre de soja Vegan Uso sugerido como un suplemento dietético tomar 1 Cápsula diaria, con o sin alimentos, o como recomendado por un nutritionally-informed médico. , o como dirigido por su profesional de la salud. Suplemento hechos servir Tamaño: 1 vcapsservings por contenedor: 60 Cantidad por servir% Valor Diario * * * bonolive (de olivo (Olea europaeal.) Leaf ext, estandarizado para contener 40% ooleuropein) 250 mg * * * Valor diario no establecido * * *% los valores diarios están basados en una dieta de 2.000 calorías Otros ingredientes: celulosa modificada (cápsula) vegetariano, microcristalino celulosa, dióxido de silicio, estearato de magnesio (Fuente vegetal) Advertencias: Mantener fuera del alcance de los niños. Como con todos los suplementos dietético, consulte a su profesional de la salud antes de su uso. Consulte la etiqueta del producto para obtener más información. .